Detalhe da pesquisa
1.
Liquid-biopsy proteomics combined with AI identifies cellular drivers of eye aging and disease in vivo.
Cell;
186(22): 4868-4884.e12, 2023 10 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37863056
2.
Macular dystrophy in Kabuki syndrome due to de novo KMT2D variants: refining the phenotype with multimodal imaging and follow-up over 10 years: insight into pathophysiology.
Graefes Arch Clin Exp Ophthalmol;
2024 Jan 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38206414
3.
Unleashing the potential of CRISPR multiplexing: Harnessing Cas12 and Cas13 for precise gene modulation in eye diseases.
Vision Res;
213: 108317, 2023 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37722240
4.
Protocol to quantify enzymatic effects on vitreous liquefaction in porcine eyes using a transwell-plate system.
STAR Protoc;
3(4): 101754, 2022 12 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36208453
5.
New COL6A6 Variant Causes Autosomal Dominant Retinitis Pigmentosa in a Four-Generation Family.
Invest Ophthalmol Vis Sci;
63(3): 23, 2022 03 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35333290
6.
Calpains as mechanistic drivers and therapeutic targets for ocular disease.
Trends Mol Med;
28(8): 644-661, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35641420
7.
Conjunctival Swabs Reveal Higher Detection Rate Compared to Schirmer Strips for SARS-CoV-2 RNA Detection in Tears of Hospitalized COVID-19 Patients.
J Clin Med;
11(23)2022 Nov 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36498504
8.
A protocol to inject ocular drug implants into mouse eyes.
STAR Protoc;
3(1): 101143, 2022 03 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35141566
9.
Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series.
Orphanet J Rare Dis;
17(1): 146, 2022 04 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35365235
10.
A Fluorescence-Based Assay to Determine PDZ-Ligand Binding Thermodynamics.
Methods Mol Biol;
2256: 137-148, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34014520
11.
Peptidomimetics Therapeutics for Retinal Disease.
Biomolecules;
11(3)2021 02 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33668179
12.
An intravitreal implant injection method for sustained drug delivery into mouse eyes.
Cell Rep Methods;
1(8)2021 12 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35128514
13.
Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.
J Clin Invest;
131(10)2021 05 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33844653
14.
A physics-based energy function allows the computational redesign of a PDZ domain.
Sci Rep;
10(1): 11150, 2020 07 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32636412
15.
Structural Insights into the Unique Activation Mechanisms of a Non-classical Calpain and Its Disease-Causing Variants.
Cell Rep;
30(3): 881-892.e5, 2020 01 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31968260
16.
SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J Cell Biol;
218(8): 2699-2725, 2019 08 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31248911
17.
Novel mutations in the 3-box motif of the BACK domain of KLHL7 associated with nonsyndromic autosomal dominant retinitis pigmentosa.
Orphanet J Rare Dis;
14(1): 295, 2019 12 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31856884
18.
A Simple PB/LIE Free Energy Function Accurately Predicts the Peptide Binding Specificity of the Tiam1 PDZ Domain.
Front Mol Biosci;
4: 65, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29018806
19.
Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.
Structure;
24(12): 2053-2066, 2016 12 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27998539